In a fight between a vampire and a werewolf, the vampire would definitely win. Although werewolves are strong and have accelerated healing abilities, they only become wolves on the night of the full moon, at which time their animal instincts take over. They may be superior in strength and fighting ability, but the vampire’s ability to calculate and strategize will win the fight.

Vampires are better equipped for the fight than werewolves because they are always vampires. Even if they go into hibernation during the day, they live with their condition all the time, while werewolves only live with it one night a month. In addition, they are fully conscious of their condition, actions, and abilities, while werewolves have the tendency to let their animal instincts take over, the human half blacking out and forgetting what the werewolf has done.

Having a better understanding of their condition and what it allows them to do, vampires are better prepared to use their skills to their advantage. They hunt nightly and know how to attract prey and drink their blood without drawing too much attention. While they may be less practiced at killing - self-preserving vampires don’t take that kind of risk so easily nowadays - they still know where to deliver a fatal wound.

Vampires also heal quickly. Werewolves heal quickly as well, but, being mortal creatures, they are less able to withstand a severe loss of blood. There is also the fact that werewolves bite to wound and kill, whereas vampires bite specifically to draw and drink blood. If a werewolf bites a vampire, the vampire will heal and still have some fight left in him. if a vampire bites a werewolf, however, the fight will soon be over. The vampire has taken the werewolf’s life force, part of his strength, and the werewolf will be left weak and unable to fight.

Finally, vampires would win against werewolves because vampires do not play by the rules. Their very existence breaks the normal rules of life and death; why would they feel bound by the rules of a fair fight? Vampires don’t even have to use their vampiric abilities to beat werewolves. Why get close enough to sink your teeth in, when you can simply fire silver bullets from a safe distance? With their hands left unable to hold a stake or a crossbow, werewolves wouldn’t stand a chance against these double-crossing vampires.